Albert Claude (24 August 1899 – 22 May 1983) was a
Belgian biologist who shared the
Nobel Prize in Physiology or Medicine in 1974 with
Christian de Duve and
George Emil Palade. He studied engineering, and then medicine (at the
University of Liège, Belgium). During the winter of 1928-29 he worked in Berlin, first at the Institut für Krebsforschung, and then at the
Kaiser Wilhelm Institute for Biology,
Dahlem. In the summer of 1929 he joined the Rockefeller Institute. While working at
Rockefeller University in the 1930s and 1940s, he used the
electron microscope to make images of
cells which deepened the scientific understanding of cellular structure and function. He discovered the chloroplasts in the cell.In 1930, Claude discovered the process of
cell fractionation, which was groundbreaking in his time. The process consists of grinding up cells to break the membrane and release the cell's contents. Claude then filtered out the cell membranes and placed the remaining cell contents in a
centrifuge to separate them according to mass. He divided the centrifuged contents into fractions, each of a specific mass, and discovered that particular fractions were responsible for particular cell functions.
In 1949, he became Director of the
Institut Jules Bordet,
Centre des Tumeurs de l'Université Libre de Bruxelles of the
Université Libre de Bruxelles (ULB) in
Brussels where he would stay until 1970.
In 1970, together with
George Palade and
Keith Porter he was awarded the......
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