Lord Francis Scott (1678–1679), died in infancy.
Lady Charlotte Scott (b. & d. 1683), died in infancy.
The Duke of Monmouth was executed in 1685 following the failure of the Monmouth Rebellion, in which he attempted to win the English throne. The duchess married Charles Cornwallis, 3rd Baron Cornwallis on 6 May 1688, but they did not have any children. Anne died in 1732, aged 80 and her titles passed to her grandson, Francis.