In or around 753, she founded the monastery of S. Michele and S. Pietro at Brescia. It later merged with that of S. Salvatore and S. Maria. After 759, she appeared frequently in Desiderius' diplomas and was probably the architect of his religious policy.
On 5 June 774, she was presented along with her husband to Charlemagne, who had conquered Pavia. She was sent with her husband and an unnamed daughter, possibly Desiderata, to Liège or Corbie, but allowed to return in 775. Paul the Deacon wrote an Epitaphium Ansae reginae praising her politics, her piety, and her beauty: coniunx pulcherrima, "most beautiful wife".
Her children with Desiderius were:
Anselperga (or Anselberga), abbess of San Salvatore