The Autovía A-45 is a highway in Andalucia, Spain. It is also known as Autovía de Malaga. It was formerly numbered N-331.
It connects Malaga to Cordoba. It heads north up the Rio Guadalmedina valley to Antequera where it has a junction with the Autovía A-92. Thereafter it is the N-331 as the road has yet to be upgraded. The dual-carriageway commences again at Benameji. It passeds the town of Lucena before joining the Autovía A-4 (N-IV) the Carretera de Andalucia south of Cordoba.