The station was opened by the LSWR in 1847. Passenger services were withdrawn in May 1969, although occasional diverted trains and railtours continued to use the line, passing through the station without calling.
Chandler's Ford was reopened for passenger traffic on 18 May 2003, although the new station building was not completed until later in the year – it was officially opened on 19 October 2003 by the television gardening presenter Charlie Dimmock, who lives in the area. The station originally had two platforms, but only one has been in use since the reopening, as the line through the station is now single-track only.
If there are engineering works at any stations between Romsey and St Denys via Southampton Central then the Chandlers Ford branch line is used by First Great Western services from Cardiff to Portsmouth or the Bristol to Brighton service.