Daniel Edward Koshland, Jr.
(30 March 1920, New York City – 23 July 2007, Walnut Creek, California) reorganized the study of biology at the University of California at Berkeley
and was the editor of the leading US science journal, Science
, from 1985 to 1995. He was a Member of the United States National Academy of Sciences.
Koshland's private fortune, derived from Levi Strauss
, put him on lists of America's wealthiest men. His early work was in enzyme kinetics
at Brookhaven National Laboratory
, Long Island, and Rockefeller University
, New York. This led him to propose the induced fit model
for enzyme catalysis
. After this advance, he turned to studying how bacteria
control their movements in chemotaxis
As chairman of the biochemistry department at the University of California at Berkeley
he reorganized the department, streamlining it along modern lines into three departments, of cell and molecular biology, integrative biology and the biology of microbes and plants.
Koshland wrote in an autobiographical article that he decided to become a scientist in the eighth grade after reading two popular books about science, Microbe Hunters
by Paul DeKruif and Arrowsmith
by Sinclair Lewis
He was married to Marian Koshland
from 1946 until her death in 1997.Thomas H. Maugh II (2007, July 26). "," Los Angeles Times
, accessed 12 Nov 2009.