From 1887 to 1902 he was a member of the Royal Society of Painter-Etchers. It was during this time that he published a number of sets of etchings (such as "The Clyde Set", "The North Holland Set" and "The North Italian Set"). In general his prints feature areas of great darkness, offset by highlights.
Cameron would later become known for his church interiors and barren landscapes of Scotland done in drypoint. The feathery lightness of these drypoints was in visual contrast with the rock and water of the subjects.
He became highly sought after by collectors, until the Great Crash in 1929 brought a collapse in prices for prints in general. He exploited his popularity by producing an unprecedented number of states of his prints, and is believed to hold the record at twenty-eight states in one case.
Cameron became a Royal Academician in 1920. He died in Perth, Scotland.