DTDP-4-dehydro-6-deoxyglucose reductase

DTDP-4-Dehydro-6-Deoxyglucose Reductase

DTDP-4-dehydro-6-deoxyglucose reductase

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In enzymology, a dTDP-4-dehydro-6-deoxyglucose reductase () is an enzyme that catalyzes the chemical reaction

dTDP-D-fucose + NADP<sup>+</sup> <math>rightleftharpoons</math> dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H<sup>+</sup>

Thus, the two substrates of this enzyme are dTDP-D-fucose and NADP<sup>+</sup>, whereas its 3 products are dTDP-4-dehydro-6-deoxy-D-glucose, NADPH, and H<sup>+</sup>.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is dTDP-D-fucose:NADP+ oxidoreductase. This enzyme is also called dTDP-4-keto-6-deoxyglucose reductase. This enzyme participates in polyketide sugar unit biosynthesis.


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