In the
fetus, the
ductus venosus shunts approximately half of the blood flow of the
umbilical vein directly to the
inferior vena cava. Thus, it allows oxygenated blood from the
placenta to bypass the
liver. In conjunction with the other fetal shunts, the
foramen ovale and
ductus arteriosus, it plays a critical role in preferentially shunting oxygenated blood to the fetal brain. It is a part of
fetal circulation.
Postnatal closure
The ductus venosus is open at the time of the birth and is the reason why umbilical vein catheterization works. Ductus venosus naturally closes during the first week of life in most full-term neonates; however, it may take much longer to close in pre-term neonates. Functional closure occurs within minutes of birth. Structural closure in term babies occurs within 3 to 7 days.
After it closes, the remnant is known as
ligamentum venosum.
If the ductus venosus fails to occlude after birth, the individual is said to have an intrahepatic
portosystemic shunt (PSS). This condition is hereditary in some dog breeds (e.g.
Irish Wolfhound). The ductus venosus shows a delayed closure in
preterm infants, with no significant correlation to the closure of the
ductus arteriosus or the condition of the infant.
See also
References
External links
- - Ductus venosus......
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