Shortly after his first wife's death, in the summer or fall of 1448, he married Katherine Howard, daughter of Robert Howard and sister of the 1st Duke of Norfolk, and they had the following children:
Catherine Nevill (b. c. 1452/bef. 1473), married Robert Tanfield (b. 1461), son of Robert Tanfield and Elizabeth Brooke, daughter of Edward Brooke, 6th Baron Cobham and Elizabeth Touchet, born c. 1433, and had issue