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Description:
EF5
is a
nitroimidazole
used in oncology research. Due to its similarity in chemical structure to
etanidazole
, EF5 binds in cells displaying hypoxia.
The
<sup>18</sup>F
-
radiolabeled
derivative
of EF5 is being studied for its possibility to be used in
positron emission tomography
(PET) to detect low levels of oxygen in
brain tumors
. This can help show how a tumor will respond to
treatment
.
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