G protein-coupled bile acid receptor

G Protein-Coupled Bile Acid Receptor

G protein-coupled bile acid receptor

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The G protein-coupled bile acid receptor is a G-protein coupled receptor which binds bile acids. One effect of this receptor is to activate deiodinases which convert the prohormone thyroxine (T<sub>4</sub>) to the active hormone triiodothyronine (T<sub>3</sub>). T<sub>3</sub> in turn activates the thyroid hormone receptor which increases metabolic rate.

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