Botha has won the Currie Cup with the Blue Bulls, the Super 14 title with the Bulls and was part of the Springbok squad that won the 2007 Rugby World Cup.
Botha made his debut for the Springboks in 2005, in a match against Australia in the Loftus Versfeld stadium in Pretoria, replacing captain John Smit.
Botha has played Rugby League for the South African Rhinos at the age of 18.