Grayslake Central, originally known as Grayslake Community High School, was built in 1949 on Lake Street. It was originally fairly small but has since expanded over the years and now includes approximately 1,400 students. The school's mascot has for years been Guido the Ram. Grayslake Community High School was renamed Grayslake Central after 2004 when Grayslake North High School was built. The school's athletic department participates in the Fox Division of the Fox Valley Conference.
Grayslake Central and Grayslake North have developed a town rivalry. This is celebrated every year with Central vs. North athletic events within the FVC Fox Division. The Grayslake North/Grayslake Central football game is called "The Kick-off Classic". The Fall of 2006 was the first year that the varsity teams were able to compete, with Central winning 33-10. In 2007 North beat Central, 31-6. The next year, Grayslake Central beat Grayslake North 33-21. In 2009, the first year in which both teams entered with a win, Central posted the first shutout in the series history in a 28-0 victory.
The 2010 edition of the football game is to date the most important game in the rivalry's history. Both teams needed a victory to keep hopes of qualifying for the state playoffs alive, and Central came out on top 34-7.