GTPase-activating protein

GTPase-Activating Protein

GTPase-activating protein

to get instant updates about 'GTPase-Activating Protein' on your MyPage. Meet other similar minded people. Its Free!

X 

All Updates


Description:
GTPase-Activating Proteins, or GAPs, or GTPase-Accelerating Proteins are a family of regulatory proteins whose members can bind to activated G protein and stimulate their GTPase activity, with the result of terminating the signaling event.Kimple, A.J. “Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)”. The Journal of Biological Chemistry. 284 (2009): 19402-19411. and these proteins are crucial in controlling the activity of G proteins. Regulation of G proteins is important because these proteins are involved in a variety of important cellular processes. The large G proteins, for example, are involved in transduction of signaling from the G protein-coupled receptor for a variety of signaling processes like hormonal signaling,Xu, Haiming et al. “Loss of the Rho GTPase Activating Protein p190-B Enhances Hematopoietic Stem Cell Engraftment Potential”. Blood. 114 (2009): 3557-3566. GAP’s role in this function is to turn the G protein’s activity off. In this sense, GAPs function is opposite that of guanine nucleotide exchange factors (GEFs), which serve to...
Read More

No feeds found

All
wait Posting your question. Please wait!...


No updates available.
No messages found
Tell your friends >
about this page
 Create a new Page
for companies, colleges, celebrities or anything you like.Get updates on MyPage.
Create a new Page
 Find your friends
  Find friends on MyPage from