Heparin cofactor II, a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate ("minor antithrombin").
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->Heparin Cofactor II deficiency can lead to increased thrombin generation and a hypercoagulable state.
The MEROPS online database for peptidases and their inhibitors:
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