The
psychedelic drug/
entheogen LSD was first synthesized by the
Swiss chemist
Albert Hofmann in the
Sandoz (now
Novartis) laboratories in Basel, Switzerland November 16, 1938. It was not until five years later on April 19, 1943, that the psychedelic properties were discovered.
Discovery
Albert Hofmann, born in Baden, Switzerland, joined the pharmaceutical-chemical department of
Sandoz Laboratories, located in
Basel as a co-worker with professor Arthur Stoll, founder and director of the pharmaceutical department. He began studying the
medicinal plant squill and the
fungus ergot as part of a program to purify and synthesize active constituents for use as
pharmaceuticals. His main contribution was to elucidate the chemical structure of the common nucleus of Scilla glycosides (an active principal of
Mediterranean Squill). While researching
lysergic acid derivatives, Hofmann first synthesized LSD on November 16, 1938. The main intention of the synthesis was to obtain a respiratory and circulatory stimulant (an
analeptic). It was set aside for five years, until April 16, 1943, when Hofmann decided to take a second look at it. While re-synthesizing LSD, he accidentally absorbed a small amount of the drug through his...
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