Lloris began his career with hometown club OGC Nice. He made his debut as a teenager in October 2005 and started in goal during the team's run to the 2006 Coupe de la Ligue Final. After excelling at the club for three seasons, Lloris moved to seven-time Ligue 1 champions Olympique Lyonnais, amid interest from several other clubs, notably Milan. Lloris won several domestic awards in his first season with Lyon and, in his second season, earned award nominations at European level for his performances in the UEFA Champions League, which saw Lyon reach the semi-finals for the first time.