In vivo selection of an entire exon

In Vivo Selection Of An Entire Exon

In vivo selection of an entire exon

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Description:
In vivo selection of an entire exon is a powerful technique used by Singh and coworkers to identify novel regulatory elements within an exonic sequence that undergoes alternative splicing. Thanks to in vivo, selection of the entire exon seven the of SMN gene, many regulatory elements have been identified. A knowledge of such elements is crucial for understanding the underlying cause of Spinal Muscular Atrophy, a devastating neuromuscular genetic disease of children and infants.

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