Knutzon is currently a member of the Asian Tour and the European Tour. He is one of few Americans who mainly play on the Asian Tour. Knutzon has been to PGA TourQualifying School once. He entered in 2000 but failed to earn a tour card. He played on the Nationwide Tour in 2001 but he only made 7 of 19 cuts and was unable to retain his card.
Knutzon joined the Asian Tour in 2003. In his rookie season he finished in 31st place on the order of merit list and recorded three top 10 finishes. In 2004 Knutzon picked up his first professional win in China at the Macau Open. Pádraig Harrington participated in the tournament and finished 3 strokes behind Knutzon. Knutzon ended up finishing in 20th place on the order of merit list which is his best order of merit finish. Knutzon picked up his second win in Indonesia at the Motorola International Bintan in 2007.