Khost University () (nickname: Shaikh Zayed University) is located in the border town of Khost in eastern Afghanistan. It was established in the year 2000. It was shifted from its previous temporary location in Peshawar, Pakistan, where it was named "Afghan University Peshawar" by special order of President Hamid Karzai.
Khost University has nine faculties and more than 3000 students. It has a private radio station for journalism faculty. It is the only university in Afghanistan with a faculty in computer science. It has a hostel for students, and medical students are trained at the government-run hospital, Khost Hospital. This university was officially opened by the United Arab Emirates officials and Khost governor in March 2008.
Khost University is one of eleven Afghan educational institutions that have e-learning labs, provided by USAID.
Khost University was built up by economical help from United Arab Emirates, that is why it's called Shaikh Zayed University.