In 1962, Sheikh Azeemi started writing articles on telepathy, parapsychology, color meditation and healing in various Pakistani newspapers and magazines. The most famous was his advice column, "Roohani Daak", in the Urdu Daily Jang. As a result of its success the Ruhani Digest was launched in 1978. He has written over 40 books, many of them having been translated into Arabic, Urdu, English, Russian and other languages.
Shaykh Azeemi is married and lives in Karachi, Pakistan with his family of nine adult children (five sons and four daughters). His eldest son, Waqar Yousuf Azeemi, Ph.D., is the current editor of Ruhani Digest and a speaker as well as an author.