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LME may refer to:

  • London Metal Exchange, the futures exchange with the world's largest market in options and futures contracts on base and other metals
  • Liquid metal embrittlement, a phenomenon where certain ductile metals experience drastic loss in tensile ductility or undergo brittle fracture when tested in the presence of specific liquid metals
  • Large marine ecosystem, a region of the world's oceans, encompassing coastal areas to the outer margins of the major ocean current systems
  • L.M.E., a fictional show business agency in the manga and anime Skip-Beat!

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