Milwaukee protocol

Milwaukee Protocol

Milwaukee protocol

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The Milwaukee protocol is an experimental course of treatment of an acute infection of rabies in a human being. The treatment involves putting the patient into a chemically induced coma and administering antiviral drugs. It was developed and named by Dr. Rodney Willoughby, Jr., M.D., following the successful treatment of Jeanna Giese.Rodney E. Willoughby, Jr., "A Cure for Rabies?" Scientific American, V. 256, No. 4, April 2007, p. 95 () Giese, a teenager from Wisconsin, became the first of only six patients known to have survived symptomatic rabies without receiving the rabies vaccine.

Case history

Initial infection

On September 12, 2004, Giese, then fifteen years old, and a student at St. Mary Springs High School, picked up a bat while attending St. Patrick's Church in her hometown of Fond du Lac, Wisconsin. She sustained a small bite on her left index finger from the animal, and having treated it with hydrogen peroxide, the family decided not to seek medical attention. Thirty-seven days after the bite, Giese developed neurological symptoms. She was admitted to St. Agnes Hospital with a fever, double vision, slurred speech, and jerking in her left arm. She did not respond to treatment and tested...
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