Neonatal hepatitis

Neonatal Hepatitis

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Neonatal hepatitis

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Neonatal hepatitis or perinatal hepatitis is a rare fulminant disease of the liver, of unknown etiology, characterized by massive deposition of iron in the liver, pancreas, heart, and endocrine glands; symptoms are those of neonatal hepatitis and appear in utero or within the first week of life, with death usually occurring by 4 months of age.

Neonatal hepatitis is histologically characterized by the presence of multinucleated giant cells. There may also be bile pigment or hemosiderin within hepatocytes.

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