Antonelli was born in Senigallia. He wrote De Titulis Quos S. Evaristus Presbyteris Romanis Distribuit (Rome, 1725), in defense of the parochial character of the primitive Roman churches. He also edited (and defended) the commentary of St. Athanasius on the Psalms, sermons of St. James of Nisibis, and under the name of Emman. S.J. de Azovedo, Vetus Missale Romanum Monasticum Lateranense (1752).