Pertussis toxin

to get instant updates about 'Pertussis Toxin' on your MyPage. Meet other similar minded people. Its Free!

X 

All Updates


Description:
Pertussis toxin (PT) is a protein-based AB<sub>5</sub>-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection.

History

Today it is clear that PT plays a central role in the pathogenesis of pertussis. However, this was only discovered in the early 1980s. The appearance of pertussis is quite recent, compared with other epidemic infectious diseases. The earliest mention of pertussis, or whooping cough, is of an outbreak in Paris in 1414. This was published in Moulton’s The Mirror of Health, in 1640. Another epidemic of pertussis took place in Paris in 1578 and was described by a contemporary observer, Guillaume de Baillou. Pertussis was well known throughout Europe by the middle of the eighteenth century. Jules Bordet and Octave Gengou described in 1900 the finding of a new “ovoid bacillus” in the sputum of a 6-month-old infant with whooping cough. They were also the first to cultivate the......
Read More

No feeds found

All
wait Posting your question. Please wait!...


No updates available.
No messages found
Suggested Pages
RRR
RRR
Tell your friends >
about this page
 Create a new Page
for companies, colleges, celebrities or anything you like.Get updates on MyPage.
Create a new Page
 Find your friends
  Find friends on MyPage from