Pterostilbene

Pterostilbene is a stilbenoid chemically related to resveratrol and is found in blueberries and grapes. It belongs to the group of phytoalexins, agents produced by plants to fight infections. Based on animal studies it is thought to exhibit anti-cancer, anti-hypercholesterolemia, anti-hypertriglyceridemia properties, as well as fight off and reverse cognitive decline. It is believed that the compound also has anti-diabetic properties, but so far very little has been studied on this issue.

Pharmacokinetics

Pterostilbene is a double-methylated version of resveratrol exhibiting a higher bioavailability as it is more easily transported into the cell and more resistant to degradation and elimination.

Pterostilbene has anti -inflammatory, antineoplastic, and antioxidant actions via modulations of gene expression and enzyme activity.

Focus of studies has been generally on the trans isomer of pterostilbene.

Animal studies

Lowering blood lipids and cholesterol

Studies that used animals fed on blueberry based diets found significant reduction in...
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