As well as appearing in many successful films, including "Mirch Masala", Ratna Pathak appeared as the wife in The Perfect Murder. She recently appeared in the hit comedy Sarabhai vs Sarabhai. She has been acting in a number of high quality comedy serials on the Indian television.
In July 2008 she appeared in the successful film Jaane Tu Ya Jaane Na as the mother of the protagonist. Naseeruddin Shah played her husband, as a deceased character who talks to her from a portrait. She has also acted in several Russian plays and as well as co-founding is an active member of "Motley Theatre Group".