Retroviral Psi packaging element

Retroviral Psi Packaging Element

Retroviral Psi packaging element

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Description:


Retroviral Psi packaging element is a cis-acting RNA element identified in the genomes of the retroviruses Human immunodeficiency virus (HIV) and Simian immunodeficiency virus (SIV) It is involved in regulating encapsidation of the retroviral RNA, an essential step in replication.

This RNA element is known to have a secondary structure composed of four hairpins called SL1 to SL4 (SL is for Stem-loop). It has been shown that SL1 may provide a secondary binding site for the viral Rev protein has been independently expressed and structurally characterised.

References



See also

Human immunodeficiency virus type 1 dimerization initiation site

Human immunodeficiency virus type 1 major splice donor

Human immunodeficiency virus type 1 stem-loop 3 Psi packaging signal

Human immunodeficiency virus type 1......
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