Mouw was Professor of Christian philosophy at Calvin College for seventeen years. He has also served as a visiting professor to the Free University of Amsterdam. He was appointed Professor of Christian Philosophy and Ethics at Fuller Theological Seminary in 1985. In 1993 he was elected president of Fuller Theological Seminary.
In 2007, Mouw was awarded the Abraham Kuyper Prize for Excellence in Reformed Theology and Public Life at Princeton Theological Seminary by the Abraham Kuyper Center for Public Theology.
Views
Dialogue with Catholics
In 2009, he signed a public statement encouraging all Christians to "read, wrestle with, and respond to Caritas in Veritate", the social encyclical by Pope Benedict XVI.