TB or Not TB

TB Or Not TB


TB or Not TB

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"TB or Not TB" is the fourth episode of the second season of House, which premiered on the Fox network on November 1, 2005. The title, "TB or Not TB", is an allusion to "To be, or not to be" from Hamlet.


Sebastian Charles (Ron Livingston) is a famous doctor who works in Africa. During a presentation to persuade companies to provide more medicine to the poor, he collapses and is taken to the hospital. Sebastian and Cuddy think he has tuberculosis (TB), but House quickly disagrees.

In Sebastian's room, Sebastian refuses to take the pills for his resistant strain of TB, hoping to bring publicity to his story and the problem with big pharmaceutical companies. House is furious at the news.

During a press conference in his hospital room, Sebastian becomes disoriented. His heart fails and Cameron tries to shock him back. House yells into one of the press cameras that Sebastian's condition isn't TB. House suggests a very tiny tumor and nesidioblastoma, which is an abnormal growth of the insulin secreting cells in the pancreas. This causes only intermittent secretion of insulin, usually in response to stress.

House and the team take Sebastian into surgery. They inject calcium into the pancreas, which will cause the beta cells to release insulin. If there are too many beta cells because of a tumor, Sebastian's blood sugar will drop quickly. The blood sugar plummets and surgery is scheduled to remove the tumor.

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