The Loin's Mouth was a semi-quarterly, Tenderloin-based publication about life in the San Francisco Tenderloin and Tendernob area. It was conceived of by its editor, Rachel M., in the Spring of 2006 and released seven issues through the Fall of 2008. Articles were generally humorous and typically revolved around a central theme of each issue, such as "Love in the Loin" (released in February 2007). Content ranged from fake news stories to editorial pieces to short stories with such titles as "One Night Stand," "Friday Night Fights," and "I, Drunkard." Contributors varied dramatically in age, background, and education. Maxon Crumb (brother of R. Crumb) had submitted several illustrations.
The Loin's Mouth was an editor's pick for "Best Neighborhood Rag" in the SF Weekly's "Best of SF" issue and won the reader's poll for "Best Local Zine (Print)" in the SF Bay Guardian's annual "Best of the Bay" issue for 2008.