Sir Upendranath Brahmachari,
KIH () (December 19, 1873 – February 6, 1946) was a noted Indian scientist and a leading medical practitioner of his time. He synthesized
Urea Stibamine (carbostibamide) in 1922 and determined that it was an effective substitute for the other
antimony-containing compounds in the treatment of
Kala-azar (Visceral leishmaniasis) which is caused by a
protozoon,
Leishmania donovani.
His discovery led to the saving of millions of lives in India, particularly in the erstwhile province of
Assam, where several villages were completely depopulated by the devastating disease. The achievement of Brahmachari was a milestone in successful application of science in medical treatment in the years before arrival of antibiotics, when there were few specific drugs, except
quinine for
malaria,
iron for
anaemia,
digitalis for heart diseases and
arsenic for
syphilis. All other ailments were treated symptomatically by palliative methods. Urea Stibamine was thus a significant addition to the arsenal of specific medicines.
Life
Upendranath Brahmachari was born on 19 December 1873 in
Jamalpur,
Bihar. Also, others claim his birthplace to be in Sardanga village near Purbasthali, District Burdwan of West Bengal, India. His father Nilmony Brahmachari was a physician in East Indian Railways. His mother's name was Saurabh Sundari Devi. He completed his early education from Eastern Railways Boys' High...
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