MRNA (guanine-N7-)-methyltransferase

MRNA (Guanine-N7-)-Methyltransferase

MRNA (guanine-N7-)-methyltransferase

to get instant updates about 'MRNA (Guanine-N7-)-Methyltransferase' on your MyPage. Meet other similar minded people. Its Free!


All Updates

In enzymology, a mRNA (guanine-N7-)-methyltransferase () is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + G(5')pppR-RNA <math>rightleftharpoons</math> S-adenosyl-L-homocysteine + m<sub>7</sub>G(5')pppR-RNA (mRNA containing an N<sub>7</sub>-methylguanine cap)

Thus, the two substrates of this enzyme are S-adenosyl methionine and GpppR-RNA, whereas its two products are S-adenosylhomocysteine and m7GpppR-RNA.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase. Other names in common use include messenger ribonucleate guanine 7-methyltransferase, guanine-7-methyltransferase, messenger RNA guanine 7-methyltransferase, and S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .


Read More

No feeds found

Posting your question. Please wait!...

No updates available.
No messages found
Suggested Pages
Tell your friends >
about this page
 Create a new Page
for companies, colleges, celebrities or anything you like.Get updates on MyPage.
Create a new Page
 Find your friends
  Find friends on MyPage from